Exercise: An Active Route to Healthy Aging Aerobic Exercise Training Increases Brain Volume in Aging Humans

نویسندگان

  • Stanley J. Colcombe
  • Kirk I. Erickson
  • Paige E. Scalf
  • Jenny S. Kim
  • Ruchika Prakash
  • Edward McAuley
  • Steriani Elavsky
  • David X. Marquez
  • Liang Hu
  • Arthur F. Kramer
چکیده

Methods. Fifty-nine healthy but sedentary community-dwelling volunteers, aged 60–79 years, participated in the 6month randomized clinical trial. Half of the older adults served in the aerobic training group, the other half of the older adults participated in the toning and stretching control group. Twenty young adults served as controls for the magnetic resonance imaging (MRI), and did not participate in the exercise intervention. High spatial resolution estimates of gray and white matter volume, derived from 3D spoiled gradient recalled acquisition MRI images, were collected before and after the 6-month fitness intervention. Estimates of maximal oxygen uptake (VO2) were also obtained.

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تاریخ انتشار 2006